this post was submitted on 23 Jan 2025
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The study Meta-Analysis of Randomized Controlled Trials of Red Meat Consumption in Comparison With Various Comparison Diets on Cardiovascular Risk Factors analyzed 6 RCT's that compared red meat to plant-based protein sources and finds that the plant-based protein sources consistently result in better blood lipids and lipoproteins compared with red meat:
As to your comments about CVD markers, there are of course contrarians, but the evidence linking both LDL-C and apoB with CVD risk is strong. Look at mendelian randomization studies for both.
https://link.springer.com/article/10.1186/s12916-020-01792-7
https://www.neurology.org/doi/full/10.1212/WNL.0000000000007091
https://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1003062
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2814089
Substitution of animal with plant protein lowers apo-B https://www.ahajournals.org/doi/full/10.1161/JAHA.117.006659
In comparison with control diets, plant-based diets improved Homeostatic Model Assessment for Insulin Resistance https://www.mdpi.com/2072-6643/16/13/2110
All cause mortality was reduced by plant-based diet in the meta-analyses of prospective cohort studies I shared earlier, nobody tries to measure that for dietary RCT’s…
Low carb diets high in animal products result in increased CAC scores and the animal-based but not plant-based LCD score is significantly associated with a higher risk of CAC progression (animal-based LCD score: hazard ratio, 1.456 [95% CI, 1.015–2.089]; P=0.041; plant-based LCD score: hazard ratio, 1.016 [95% CI, 0.821–1.257]; P=0.884 https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.120.314838 (observational)