Me preparing my teaching using Emacs/org-mode. I don't know any other software that gives me this perfect balance between eye candy (although I had to work for that) and extreme usability. I mean, sure, TeXmacs or LyX may make the notes even a bit prettier, but good luck navigating them or using those for organization of, like, anything.
Well there's the teensy-weensy difference that emacs/org is designed with effective navigation and organization as two of its main purposes, while TeXmacs or LyX are built for different purposes and have no ambition of shifting their scope to navigation/organization.
Like... PowerPoint is Turing complete so I could just use that too, but there's a reason I don't use that for coding or project management and it's not just that I'm conservative...