I do! Since a while I selfhost with my risc-v Unmatched board. There are prebuilt Ubuntu Server images available. Its mainly for software which you have the source code for, and are willing to build from source. I've made use of docker buildx for cross cmpilation a fair bit as well. Go and Rust has good support. A good start can be to check out the riscv-bringup repo from carlosedp. Its definitely early days though, you need to be pretty motivated. Debian support is scheduled for next year AFAIK.
So, what do I actually use it for? nginx + tailscale so far
I should say as well, postgres, mariadb and memcached all support riscv, you just got to build it yourself. I have found the riscv64 ubuntu docker images useful as well to use as a base - for example the riscv64/ubuntu one.