Edit: Probably try @nanook@friendica.eskimo.com's solution of systemctl daemon-reload
first.
Yes. When booting, your system has an initial image that it boots off of before mounting file systems. You have to make sure the image reflects the updated fstab.
On another note, for actually doing it, it looks like Fedora uses Dracut, so you just need to run
sudo dracut -f
.