187
submitted 5 months ago by ZeroCool@slrpnk.net to c/science@mander.xyz
top 33 comments
sorted by: hot top controversial new old
[-] GrymEdm@lemmy.world 67 points 5 months ago

Super interesting! I'm going to file this under "hope it's true, will wait for testing/confirmation because the claims are amazing".

[-] itsnicodegallo@lemm.ee 11 points 5 months ago

Note that some studies show nine mouse days are roughly equivalent to one human year.

Excuse me?

[-] jol@discuss.tchncs.de 14 points 5 months ago

Basically mice procrastinate much less than people.

[-] runner_g@lemmy.blahaj.zone 7 points 5 months ago

Given the position of this statement in the article, I'm guessing they are trying to imply a correlation in rate of aging. Like 1 dog year = 7 human years. They are further implying that if a mouse maintains immunity for 90 days, a human would maintain immunity for 10 years.

It should be clear that it is the reporter stating this, not the original authors of the study.

[-] Pyr_Pressure@lemmy.ca 4 points 5 months ago

I'm no cell biologist but I don't think immunity works that way. I don't know enough to dispute it though.

[-] runner_g@lemmy.blahaj.zone 6 points 5 months ago

I am a molecular biologist, and it kinda works this way. B cells are called memory cells because they hold onto that "memory" of the invader for a really long time. You probably haven't had an MMR or a Tetanus vaccine in 10+ years because the body is really good at remembering. But we have to get flu boosters every year because the flu mutates so rapidly that traditional b cells won't recognize the flu after a year of mutating. (RNA viruses can't correct their mutations so they change much faster than bacteria or DNA viruses). RNAi was still pretty new when I was in school and I haven't kept up with the research so I can't speak to it's effectiveness at long term immunity.

[-] Pyr_Pressure@lemmy.ca 3 points 5 months ago

I know enough about that, the part I was skeptical about though was the assumption that if a mouse is immune for 90 days, a human would be immune for 10 years.

[-] runner_g@lemmy.blahaj.zone 1 points 5 months ago

And you are absolutely right to be skeptical about that, that is a crazy level of extrapolation.

[-] Anticorp@lemmy.world 1 points 5 months ago

It is good that you recognize that you don't know enough to dispute it. Now just recognize that people who do know enough aren't disputing it.

[-] kemsat@lemmy.world -1 points 5 months ago

I assumed it had to do with heartbeats. Mice hearts beat much faster than human hearts, and I think of the heartbeat like a computer’s clock or an engine’s RPM. If you increase that, the rate of everything else increases.

[-] Daxtron2@startrek.website 4 points 5 months ago

You're excused

[-] prole@sh.itjust.works 4 points 5 months ago

I thought the thumbnail was a Smurf hand holding a crackpipe... I think I need to get more sleep.

[-] Anticorp@lemmy.world 2 points 5 months ago

Or possibly less crack.

[-] Reddfugee42@lemmy.world 3 points 5 months ago

So I can stop drinking bleach?

[-] Anticorp@lemmy.world 2 points 5 months ago

No more light bulbs up the arse either.

[-] clay_pidgin@sh.itjust.works 3 points 5 months ago

Aww man, there go my weekend plans.

[-] Anticorp@lemmy.world 2 points 5 months ago

Well, you can still do it if you enjoy it.

this post was submitted on 18 Apr 2024
187 points (99.0% liked)

Science

3072 readers
14 users here now

General discussions about "science" itself

Be sure to also check out these other Fediverse science communities:

https://lemmy.ml/c/science

https://beehaw.org/c/science

founded 2 years ago
MODERATORS