In other news, blood Is red. Jk. In all seriousness we have known aspartame causes issues for awhile now
this post was submitted on 29 Jun 2023
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Causes it, or possibly causes it? Seems like they should get their ducks in a row and find out conclusively?
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I am curious whether this will actually impact what is considered safe to consume on a daily basis.
Again, many things are unhealthy and carcinogenic in large quantities. The infamos study showed that Aspartame was causing cancer in mice but the amounts they were given would be like humans eating bags of it every day.
This post might get buried, but I feel it needs to be said.
N-methyl-D-aspartate (NMDA) receptor agonists cause excitoxity, resulting in neuronal death:
NMDA and Glutamate Evoke Excitotoxicity at Distinct Cellular Locations in Rat Cortical Neurons In Vitro / "We hypothesized that exogenous glutamate is toxic neu- rons under these circumstances by activating somatic receptors exclusively (Speliotes et al., 1994). In the present study, we provide experimental evidence that directly supports this hypothesis."
Asparatame binds to NMDA sites:
Effect of aspartame on N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain synaptic membranes "These in vitro findings suggested that aspartame may act directly on the N-methyl-D-aspartate-sensitive glutamate recognition sites in the brain synaptic membranes."
There are many sources which indicate that aspartame also compromises the blood-brain barrier, which is not exactly a good thing (e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617129/)
Make of this what you will, but our brains produce as much glutamate as we need. In case of head trauma such as stroke, it produces too much, which results in cell death and probably a lot of the disability following a stroke.
I don't think we need any extra NMDA agonists in our diet, but then again I'm just a layman in this area.
For context, this is the same designation that bacon currently has, amongst a whole bunch of other things we all eat.
Yeah, but bacon is probably like the unhealthiest meat you can eat. Its packed with sodium nitrites to retain its pink hue and is absolutely off the charts for actual sodium content as well as saturated fat, which makes up nearly 70% of its calories. If you were eating a 1kg pack of bacon the way I see people chugging a daily liter o cola, it would be incredibly unhealthy.
I'm not sure because I think more studies need to be done.
What I do know is I never liked diet coke or anything with artificial sweeteners. Never drank them. But when I got cancer I craved it. During chemo it was the only thing I could drink without issue. So there's that.
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Hasn’t it already been proven to facilitate the development of Alzheimer? Honest question - I’m a layman in medicine and just worried about my dad chugging tons of diet products full of aspartame, thinking it’s the healthy choice (as opposed to non-diet lemonade for instance).
I don't know enough to disqualify the studies they cite, but I guess at least these folks seem to be the opposite of industry shills? There is an Alzheimer's section. US Right to Know: Aspartame
The Alzheimer's Association (safely covering their asses) defers to the FDA's approval but does note concerns have been raised. it's myth 5 here