I switched to Linux while going back to school in 2014.
My calculus class had one of those "buy the $80 textbook to get the code for the online assignments" things which didn't want to work in Linux. I think the URL had something to do with Wolfram. Figures. Side question: Do they still give out copies of Mathematica to Raspberry Pi owners?
Turns out English professors can't tell the difference between Times New Roman and Liberation Sans.
Writing papers in LibreOffice Writer isn't a problem, it works fine for that. My professors tended to want them printed out and turned in on paper, so they had no clue what software made it. Printing to PDF works perfectly well too; if they specifically want a .docx file you'll probably survive. I would probably recommend OnlyOffice over LibreOffice for MS Office compatibility, but an MLA formatted school essay should survive that conversion.
The least plausible thing was working with other students on PowerPoint presentations. LibreOffice Impress works well enough, you can put words and pictures on slides, but its compatibility with PowerPoint just ain't there. "Let's each make five slides." maybe if you work with a blank template first, collect them all together, then apply a style.