So you wouldn’t laugh at someone wearing clown makeup but otherwise acting serious?

I would assume they worked as a clown or something similar and were on their break. Also, clowns aren't funny.

I say fair game to anyone that intentionally alters their appearance in a stupid way.

What you consider to be stupid is subjective. But you're free to laugh at people all you want. Just like how other people can think you're not a very good person for doing so.