this post was submitted on 09 Nov 2023
845 points (98.1% liked)
Comic Strips
12619 readers
3080 users here now
Comic Strips is a community for those who love comic stories.
The rules are simple:
- The post can be a single image, an image gallery, or a link to a specific comic hosted on another site (the author's website, for instance).
- The comic must be a complete story.
- If it is an external link, it must be to a specific story, not to the root of the site.
- You may post comics from others or your own.
- If you are posting a comic of your own, a maximum of one per week is allowed (I know, your comics are great, but this rule helps avoid spam).
- The comic can be in any language, but if it's not in English, OP must include an English translation in the post's 'body' field (note: you don't need to select a specific language when posting a comic).
- Politeness.
- Adult content is not allowed. This community aims to be fun for people of all ages.
Web of links
- !linuxmemes@lemmy.world: "I use Arch btw"
- !memes@lemmy.world: memes (you don't say!)
founded 1 year ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
There are a variety of ways in which our bodies attune to constant stimulus, in the case of neural stimulus, there are a variety of mechcanisms with the common goal of reducing activation of the neural pathway. You could have less receptors, more breakdown of the stimulating compound, increased cell activation treshold or downstream changes that similarly just reduce the ability for the signal to cause effects further along the chain.
Receptor or physical clogging generally (afaik) does not happen with substances we encounter normally, however it is a common tactic in pharmacology, where we might use a drug that binds to a receptor without effect and prevents the active compound from binding.
Or in the case of Succinylcholine, it binds, causes the normal action, but then prevents the normal molecule from binding and causing the action again - this is used to achieve rapid muscle paralysis and is both a poison as well as a common drug used for anesthesia.