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Incidentally, the US FDA has just completed updated studies on phenylephrine, more rigorous than when it was first introduced, and determined that when taken orally it is fully metabolized before it makes it to the sinuses and is completely ineffective. It's going to disappear from shelves soon.
Which is something anyone who needed psuedoephedrine but got phenylephrine could have told them decades ago.
Good to know and yes I've been seeing reports on this.
~~But they also found that phenylephrine works amazingly well when used as a nasal spray, which they didn't quite know before. ~~
Incorrect, see comment: https://lemmy.world/comment/4577725
Do you have a source for that? My understanding is that the recent review looked only at oral usage and made no determination on its efficacy as a nasal spray.
I recall reading it somewhere when the news was first coming out that it was useless as an oral medicine- lemme see if I can find it again.
Edit: I musta misread whatever news article it was - I just skimmed the actual release from the FDA and don't really mention the nose spray route at all. https://www.fda.gov/media/171972/download
Thanks for checking!