Asklemmy

It straight up reads like cult craziness or crazy 2 am infomercials. HEAD ON! APPLY DIRECTLY TO FOREHEAD! I'm glad you've placebo'd yourself into happiness though lol.

You said Exercise grows your hippocampus in 4 different bullet points lmfao. Great, it increases size by 2%. It proves nothing about whether it affects depression in adults. In fact, the studies show they do jack shit except help memory lol.

Exercise training increased hippocampal volume by 2%, effectively reversing age-related loss in volume by 1 to 2 y.

More showing it means little to nothing:

https://www.sciencedirect.com/science/article/pii/S1053811917309138

https://www.frontiersin.org/articles/10.3389/fphys.2017.00085/full

The effect of aerobic exercise on hippocampal volume in patients with psychotic disorders

Four studies examined the effect of aerobic exercise on hippocampal volume in people with schizophrenia or first episode psychosis (n = 107). Aerobic exercise did not significantly increase total hippocampal volume compared to control conditions (g = 0.149, 95% CI: -0.31 to 0.60, p = 0.53, Table 2). Among the two studies which reported effects on left/right hippocampus separately, there was no evidence of effects in either region (both p > 0.1). There was also no evidence of heterogeneity or publication bias influencing these results.

The effect of aerobic exercise on hippocampal volume in other populations

Data in other populations was insufficient for pooled meta-analyses, and so results from individual trials are summarised below. Individual trials which examined effects of aerobic exercise in patients with depression (Krogh et al., 2014), mild cognitive impairment (Brinke et al., 2014) and probable Alzheimer's disease (Morris et al., 2017) all found no significant effects on total or left/right hippocampal volumes. One study examining the effects of exercise in young-to-middle-aged adults found no change in total hippocampal volume but did find a significant increase in anterior hippocampal volume following 6 weeks of aerobic exercise (Thomas et al., 2016).

Effects of exercise in relation to participant age

Meta-regression analyses were performed to examine the relationship between mean sample age and effects of exercise on hippocampal volume. No statistically significant associations of effects of exercise with sample age were found for total, right or left hippocampal volume (all p > 0.05).

In conclusion, this meta-analysis found no effects of exercise on total hippocampal volume, but did find that exercise interventions retained left hippocampal volume significantly more than control conditions. As these positive effects were also observed among the subgroup of studies of healthy older adults, the findings hold promising implications for using exercise to attenuate age-related neurological decline. Currently, the overall quality of the evidence is compromised by the fact that 10 of the 12 studies included some risk of bias, therefore more high-quality RCTs are now required. In additional to RCTs, a prospective meta-analysis examining how changes in physical activity and fitness predict hippocampal retention/deterioration across the lifespan would provide novel insights into longer-term neural effects of exercise, while also reducing the impact of methodological heterogeneity often found across exercise RCTs. Further research is also required to determine effects in younger people (Riggs et al., 2016), and establish the neurobiological mechanisms through which exercise exerts these effects, in order to design optimal exercise programs for producing neurocognitive enhancements. However, the functional relevance of structural improvements has also yet to be ascertained. Nonetheless, the link between cardiorespiratory fitness with both structural and performance increases indicates this as a suitable target for aerobic training programs to improve brain health.