this post was submitted on 24 Jun 2023
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[–] Neuron@lemm.ee 22 points 1 year ago (2 children)

https://www.factcheck.org/2021/05/the-wuhan-lab-and-the-gain-of-function-disagreement/

Above is a good summary. Here's my personal take if interested:

Short story is an nih grant was awarded to a US based non profit research coalition, and the grant involved collaboration among multiple institutes. NIH funds are generally given to US based researchers primarily, but it's also common if you have a good reason for the project to have international collaboraters on the grant as well. In this case they were collaborating with the Wuhan virology institute, who are obviously going to be very helpful in any collaboration to study corona viruses, since multiple novel corona viruses have been found or made the jump to humans in China before. So yes, a small portion of a much larger grant was sent to Wuhan, who helped provided corona virus samples for US researchers to study.

As an aside it's also mentioned there was another corona virus 96% similar in genome to covid was previously isolated by that lab from bats. But saying that's proof they artifically made covid from that virus is pretty ridiculous, altering genomes to that extent and still having a functioning virus is basically science fiction, would take an absurd amount of technology and resources that just do not exist currently. For comparison, humans and chimpanzees have 98.8% similar genomes, so 96% is really not that close. To get from 96% similar to covid even in the much smaller viral genome would still involve at least 1200 changes to different nucleotides across every gene and structural non coding regions and still have all the proteins it encodes not only somehow still work and be expressed correctly but do this even better than before. We're struggling along with just slight changes to one gene at a time in genetic engineering currently.

Another point that keeps coming up, is research that was done in North Carolina (not China) that some people argue as gain of function research but by other definitions is not (if nih considered it gain of function research it would not have been funded due to a funding pause with that). This keeps being conflated with US funding gain of function research in China, which is not the case.

All in all, the NIH was absolutely interested in funding research into corona viruses because of the fear that something like this would happen after multiple novel corona viruses that started pandemics. I'm still very skeptical of the lab leak theory personally, when we already have multiple instances of novel corona viruses causing epidemics lately, like obviously it could happen again and still can. I suppose it's possible this virus was found somewhere else, then brought to the lab, then leaked from the lab, but then it would have already been circulating and could have caused a pandemic anyways even without a lab leak. I think people just want to have an easy answer or someone to clearly blame, when the whole world is actually to blame for some extent with out terrible responses to potential pandemics and actually chronic underfunding to this problem that should be a high priority for the whole world. And probably will be happening with only greater frequency as we encroach further on habitats and become more and more densely populated and interconnected. Saying oh we just need to lock down viral labs even more (which hey I'm not even saying is a bad idea, keep that stuff locked up tight), is a much simpler problem to tackle so people would rather go after that than the true larger issues we're facing with our poor abilities to surveil for and respond to potential pandemics.

Hope some found that interesting at least, sorry for the novel.

[–] cookiedillo@beehaw.org 8 points 1 year ago

You answered my question perfectly! Thank you for the novel.

[–] brihuang95@sopuli.xyz 2 points 1 year ago

The novel is okay, great read and I definitely learned something!