this post was submitted on 26 Jan 2025
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@Etterra it is not 100% clear yet, but the process is as follows:
All males convert testosterone into DHT, a more potent version of itself, using 5-alpha-reductase. This DHT causes, in follicles which are susceptible to it, the hair strand to become thinner and thinner, untill it eventually disappears.
Usually, these sensitive follicles are only at the top, which is why a transplant works: it moves unsensitive follicles to the top, and they will keep on producing hair despite DHT
IIRC, there is also a version of 5-alpha-reductase that is precisely more active on the top, which might help bald even more. It gets blocked with dutasteride / propecia