Every so often it seems like the pill isn't really doing it's job. I start to wonder if I'm building up a tolerance, and need to ask for an increased dosage, and then suddenly I'm doing fine again.

Well, I was going through that recently, and I realized I just switched to my newest bottle. Now it feels just as strong, if not stronger than it used to be. As it happens, I tend to have some spares from days I forget and whatnot, so it's been maybe 2 weeks. That also means this last bottle was over month old, too. I wish I could remember if I'd just changed to the new bottle the last time this happened too.

I'm using Walgreens, and the shape of the pill changed last month, so maybe there's a different formulation? I just keep going through this feast and famine of medication efficacy, and Itd be nice to know if this is a problem I can actually solve without going to a higher dosage. Idk, maybe I'll keep them in the fridge while Im not using them or something.

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[–] frogfruit 1 points 1 year ago* (last edited 1 year ago)

My doctor said sometimes certain stimulants can just stop working after a while and that supposedly it's not the same as tolerance. You should definitely discuss these concerns with your Doctor.

If you are AFAB, then it could be fluctuating hormones. I have noticed that my medication is much less effective during the luteal phase of my menstrual cycle. Diet and sleep can also alter effectiveness.

It is possible that certain formulations in certain brands have fillers that are interfering with your absorption/metabolism, but this is supposedly extremely unlikely. Pharmacies also tend not to like when you prefer certain brands of generics, and it would likely make it much more difficult to obtain your meds if you asked. With the shortage, they most likely don't have multiple brands of generics on hand anyway.