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Anime avatars are often a coin toss between (potential) comrade and chud, so it may be fun and maybe helpful to think about and share those in the place of that old 
bellwether for chuddery.
Mine is anyone with ".eth" as a suffix in their online name. I have yet to see a single person that does that that isn't a chud. 
It may even be cheating, but seeing an actual cryptofascist cartoon "original NFT do not steal" is a pretty reliable red flag too. 
EDIT: Oh yeah, I almost forgot. 
I'm too lazy to scroll through this thread rn, but nothing non-chuddy has ever been posted on Twitter by someone whose username is just a first name and a bunch of random numbers. There's even a funny tweet about this phenomenon.
There's a pretty good chance that those accounts are feds, bots, or bots run by feds. So yeah, checks out.