this post was submitted on 31 Jul 2023
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"New Vaccine Targets Alzheimer’s Disease at its Roots"

#Alzheimer #Disease #Vaccine #Health #Aging #Science #Technology #News

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[–] NotAnonymousAtAll@feddit.de 29 points 1 year ago (1 children)
[–] NotAnonymousAtAll@feddit.de 33 points 1 year ago (1 children)

TL;DR: Looks promising in mice, not tested in humans yet.

[–] Steve@compuverse.uk 4 points 1 year ago

Slightly longer AI summary by Kagi

Researchers have developed a novel vaccine that targets senescence-associated glycoprotein (SAGP) expressed in inflamed brain cells linked to Alzheimer's disease. When tested in mice, the vaccine reduced amyloid deposits, decreased inflammatory biomarkers, and improved the animals' awareness of their surroundings. This suggests the vaccine may lessen disease symptoms. The vaccine targets activated microglia cells which play a role in brain inflammation that can worsen cognitive decline. By removing toxic microglia, the vaccine may control inflammation and ultimately repair deficits suffered in Alzheimer's disease. If successful in humans, the vaccine could be a major step forward in delaying or preventing the disease.