For all my non-compliant, non-supported hosts I started using Fedora CoreOS quite successfully.
If you package your applications as containers, you should have a very easy time with it. It's based off ostree, which means a couple of things:
- immutable (so not easy to break, I guess?)
- atomic upgrades, which means you upgrade in a single step
- atomic and full rollbacks, which means if an upgrade breaks your host, you can rollback to the exact previous version booted simply by choosing it from grub
- still based on rpm, so you will still have a grasp of it, even though many things are completely different
- other benefits I forgot, I'm sure :)
All with the added benefit that once you go towards containers you can change your distro with minimal effort, so there's that.