I mean....
Steam? Maybe? I dunno, I don't game but the Steam kids seem to prefer Arch. I'm sure they have their reasons.
Practically? Probably nothing terribly significant.
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Linux is a family of open source Unix-like operating systems based on the Linux kernel, an operating system kernel first released on September 17, 1991 by Linus Torvalds. Linux is typically packaged in a Linux distribution (or distro for short).
Distributions include the Linux kernel and supporting system software and libraries, many of which are provided by the GNU Project. Many Linux distributions use the word "Linux" in their name, but the Free Software Foundation uses the name GNU/Linux to emphasize the importance of GNU software, causing some controversy.
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I mean....
Steam? Maybe? I dunno, I don't game but the Steam kids seem to prefer Arch. I'm sure they have their reasons.
Practically? Probably nothing terribly significant.
I'm a complete noob in the games department. Btw, I see that you don't use Arch.
Natively install RPM packages? Really, there's not much. Find a setup that you like.
I had trouble using Flatseal to adjust permissions for Flatpak applications in Linux Mint. But that was a few months ago and may have been fixed. Other than that I never really had trouble with stuff being broken or unavailable in Mint.
I guess if you use very new hardware you might prefer a newer kernel than the one Mint uses. Or if you want the latest versions of packages, a rolling distro might suit you better. Or you might prefer a different filesystem. But if none of this bothers you, there's no need to switch. Mint generally works well.