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I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.
I consider this the closest thing to a "cure" for drinking problems but it required discipline and it doesn't prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session
Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/