this post was submitted on 01 Aug 2023
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I'm currently on a preventative medication called Vyepti and 5 mg nasal zolmitriptan for those pop-up cases.
Those two medications have literally changed my life, I went from 8 - 10 absolutely crippling migraines to 3 - 4 easily saved off with a dose of zolmitriptan.
Good to hear those are helping you! I'm actually on a couple preventatives currently, Aimovig 70mg and Amitriptyline 30mg, and then Ubrelvy for those pop-up cases as needed. They haven't been perfect, but pretty awesome. I used to have headaches and/or migraines almost daily. Now I am down to maybe a couple times a month, and typically much less severe. Looking at upping the dose of the Aimovig as that has had the biggest impact. Hopefully doing so will help even further reduce it all.
Yes, much like you I had crippling migraines nearly everyday. I dtried Amitriptyline but it really didn't help. Switched to topiramate which improved things dramatically but the long term side effects of that were unbearable. Then moved to Vyepti about two months ago.
How has the Vyepti been helping out? Depending on how things go when we up the Aimovig, I might consider switching. Overall it's been pretty great though, so I don't want to switch away from it yet. No huge side effects and for the most part it's been pretty effective.
I've only had the one dose of it. Next one is due later this month but tbh it's been great so far.
No side effects so far which is nice as I have had varying side effects from all the meds I've taken so far.